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You are here: Home / Lifestyle / Best vitamin supplements for anxiety and depression

Best vitamin supplements for anxiety and depression

Are you seeking for the best vitamin supplements for anxiety and depression on the market? If you answered yes, you are lucky because you have arrived at the greatest possible spot.

There are many different types of vitamin supplements for anxiety and depressions to choose from, so it can be tricky to decide which one is right for you. To help you make your decision, we’ve put together a list of the 10 best vitamin supplements for anxiety and depression on the market.

We’ve included a variety of options and price points to suit every budget and need. Whether you’re looking for a budget or the highest quality vitamin supplements for anxiety and depression, we’ve got you covered. So, if you’re in the market for a new vitamin supplements for anxiety and depression, read on for our top 10 picks.

10 Best vitamin supplements for anxiety and depression: Editor Recommended

# Preview Product Price
1 OLLY Hello Happy Gummy Worms, Mood Balance Support, Vitamin D, Saffron, Adult Chewable Supplement, Tropical Zing - 60 Count OLLY Hello Happy Gummy Worms, Mood Balance Support, Vitamin D, Saffron, Adult Chewable Supplement,... $13.19Amazon Prime Buy on Amazon
2 Zen Again Cortisol Manager with Ashwagandha KSM-66 | Cortisol Supplements for Women ​| 11-in-1 Complex | Natural Stress Support Supplement with L-Theanine, Rhodiola & Magnesium | Vegan, 60 Ct Zen Again Cortisol Manager with Ashwagandha KSM-66 | Cortisol Supplements for Women ​| 11-in-1... $27.95Amazon Prime Buy on Amazon
3 OLLY Hello Happy Gummy Worms, Mood Balance Support, Vitamin D, Saffron, Adult Chewable Supplement, Gluten Free, Tropical Zing - 90 Count OLLY Hello Happy Gummy Worms, Mood Balance Support, Vitamin D, Saffron, Adult Chewable Supplement,... $19.78Amazon Prime Buy on Amazon
4 NOW Supplements, True Calm, with Magnesium, GABA, B Vitamins & More, 90 Veg Capsules NOW Supplements, True Calm, with Magnesium, GABA, B Vitamins & More, 90 Veg Capsules $11.99Amazon Prime Buy on Amazon
5 Built by Nature Calm+ Relaxation & Focus – Stress, Cortisol & Mood Support – Calm Supplement with L-Theanine, Ashwagandha, Magnesium Glycinate, Vitamin D3 – 90 Capsules Built by Nature Calm+ Relaxation & Focus – Stress, Cortisol & Mood Support – Calm Supplement... $19.99Amazon Prime Buy on Amazon
6 Energy & Mood Supplement – Boost Energy & Reduce Fatigue, Support Relaxation – 60 Capsules – Non-GMO, 3rd Party Tested – Innervis Nutrition Energy & Mood Supplement – Boost Energy & Reduce Fatigue, Support Relaxation – 60 Capsules –... $7.49Amazon Prime Buy on Amazon
7 Calmable Stress Relief Aid for Teens - Vegan - Pyridoxine B6, L-Theanine - Vitamin Dietary Supplement - 60 Capsules Calmable Stress Relief Aid for Teens - Vegan - Pyridoxine B6, L-Theanine - Vitamin Dietary... $17.99Amazon Prime Buy on Amazon
8 Habit Stress Relief Supplement (60 Capsules) - New Look, Supports Relaxation & Mood Balance, Vitamin B, Adaptogens, Lemon Balm, Calming, Vegan, Non-GMO (1 Pack) Habit Stress Relief Supplement (60 Capsules) - New Look, Supports Relaxation & Mood Balance, Vitamin... $9.94Amazon Prime Buy on Amazon
9 5-HTP Formula for Stress Relief and relaxation support for Teens and Adults with 5-HTP, L-Theanine, Vitamin B6, Vitamin B12, Magnesium - Doctor Formulated - Magnesium Stearate Free - 60 capsules. 5-HTP Formula for Stress Relief and relaxation support for Teens and Adults with 5-HTP, L-Theanine,... $19.99Amazon Prime Buy on Amazon
10 DR. EMIL NUTRITION 200 MG 5-HTP Plus with SAM-e for Mood, Stress, and Sleep - 5HTP Supplement with Vitamin B6-120 Vegan Capsules, 60 Servings DR. EMIL NUTRITION 200 MG 5-HTP Plus with SAM-e for Mood, Stress, and Sleep - 5HTP Supplement with... $37.60Amazon Prime Buy on Amazon

Our Editor’s 10 Best vitamin supplements for anxiety and depression Reviews

SaleBestseller No. 1
OLLY Hello Happy Gummy Worms, Mood Balance Support, Vitamin D, Saffron, Adult Chewable Supplement, Tropical Zing - 60 Count
OLLY Hello Happy Gummy Worms, Mood Balance Support, Vitamin D, Saffron, Adult Chewable Supplement, Tropical Zing - 60 Count
  • ADULT GUMMY WORM SUPPLEMENT: These wiggly little guys deliver a delightful dose of cheer to help you feel upbeat. The star of the show? Highly-prized Saffron, coveted for its powerful mood-balancing properties*
  • THE GOODS INSIDE: Saffron helps boost serotonin for those feel-good vibes. It’s paired with Vitamin D, a happy mood’s bestie that goes straight to the source to support cellular and brain health, and provide antioxidant benefits*
  • HOW TO TAKE: Chew two gummy worms daily for best results, no food or water needed. 60 gummies per bottle (30-day supply)
  • NATURALLY DELICIOUS: These mood support OLLY gummies come in naturally flavored Tropical Zing (a lively blend of pineapple, peach and orange) with no artificial colors or flavors and gluten-free.
  • MIX AND MATCH: Delightful and delicious OLLY products can be taken together—mix and match as you please
$13.19 Amazon Prime
Buy on Amazon
Bestseller No. 2
Zen Again Cortisol Manager with Ashwagandha KSM-66 | Cortisol Supplements for Women ​| 11-in-1 Complex | Natural Stress Support Supplement with L-Theanine, Rhodiola & Magnesium | Vegan, 60 Ct
Zen Again Cortisol Manager with Ashwagandha KSM-66 | Cortisol Supplements for Women ​| 11-in-1 Complex | Natural Stress Support Supplement with L-Theanine, Rhodiola & Magnesium | Vegan, 60 Ct
  • [Plant-Based Cortisol Support] Zen Again cortisol detox features KSM-66 Ashwagandha for women and men, a clinically studied adaptogen used to support healthy cortisol levels. This premium root extract helps your body manage stress naturally, promoting calm energy and daily balance without harsh stimulants or sedatives.*
  • [Adaptogen Blend for Resilience] Formulated with Rhodiola Root, Panax Ginseng, and Holy Basil, Zen Again cortisol supplement for men and women helps support the body’s natural stress response. These adaptogens work synergistically to promote emotional balance, mental clarity, and energy under pressure.* ​
  • [Promotes Relaxed Focus] L-Theanine, paired with Phosphatidylserine, helps support calm alertness without drowsiness. Whether you're working, parenting, or juggling multiple priorities, Zen Again helps you stay composed and present during everyday stress.* ​
  • [Supports Restful Sleep] With ingredients like Magnolia Bark and L-Glycine, this formula supports a calm nighttime routine and better sleep quality. Designed for flexibility, Zen Again can be taken morning or evening—without causing next-day grogginess.*
  • [Magnesium & B6 for Nerve Health] Magnesium Glycinate and Vitamin B6 play a critical role in stress regulation and neurotransmitter support. This calming mineral and essential vitamin duo helps ease tension while supporting mood stability and muscle relaxation.* ​
$27.95 Amazon Prime
Buy on Amazon
SaleBestseller No. 3
OLLY Hello Happy Gummy Worms, Mood Balance Support, Vitamin D, Saffron, Adult Chewable Supplement, Gluten Free, Tropical Zing - 90 Count
OLLY Hello Happy Gummy Worms, Mood Balance Support, Vitamin D, Saffron, Adult Chewable Supplement, Gluten Free, Tropical Zing - 90 Count
  • ADULT GUMMY WORM SUPPLEMENT: These wiggly little guys deliver a delightful dose of cheer to help you feel upbeat; The star of the show? Highly-prized Saffron, coveted for its powerful mood-balancing properties
  • Product Note: Exposure to heat or sunlight may lead to melting/damage of product; Hence customers are expected to be available during the product delivery
  • THE GOODS INSIDE: Saffron helps boost serotonin for those feel-good vibes; It’s paired with Vitamin D, a happy mood’s bestie that goes straight to the source to support cellular and brain health, and provide antioxidant benefits
  • HOW TO TAKE: Chew two gummy worms daily for best results, no food or water needed. 90 gummies per bottle (45-day supply)
  • NATURALLY DELICIOUS: These mood support OLLY gummies come in naturally flavored Tropical Zing (a lively blend of pineapple, peach and orange) with no artificial colors or flavors and gluten-free
$19.78 Amazon Prime
Buy on Amazon
SaleBestseller No. 4
NOW Supplements, True Calm, with Magnesium, GABA, B Vitamins & More, 90 Veg Capsules
NOW Supplements, True Calm, with Magnesium, GABA, B Vitamins & More, 90 Veg Capsules
  • A combination of amino acids and their cofactor nutrients formulated to support the normal production and function of calming neurotransmitters in the brain*
  • Includes GABA and glycine, two amino acids that promote a relaxed state of mind as well as taurine, another amino acid with calming properties*
  • Blended with valerian, which is known to interact with the GABA receptors in the nervous system*
  • Take 1 capsule 1 to 3 times daily, preferably on an empty stomach or just before meals
  • Packaged in the USA by a family owned and operated company since 1968
$11.99 Amazon Prime
Buy on Amazon
Bestseller No. 5
Built by Nature Calm+ Relaxation & Focus – Stress, Cortisol & Mood Support – Calm Supplement with L-Theanine, Ashwagandha, Magnesium Glycinate, Vitamin D3 – 90 Capsules
Built by Nature Calm+ Relaxation & Focus – Stress, Cortisol & Mood Support – Calm Supplement with L-Theanine, Ashwagandha, Magnesium Glycinate, Vitamin D3 – 90 Capsules
  • Promotes Relaxation and Focus: Formulated with L-Theanine and Ashwagandha to support a calm mind and boost mental clarity.
  • Supports Stress: Help balance cortisol, aiding your body's natural response to stress.
  • Mood and Wellness: Includes Magnesium Glycinate and Vitamin D3 to contribute to overall mood.
  • Natural Ingredients: Crafted with high-quality, non-GMO ingredients to foster a focused mindset
  • More Convenient Than a Drink Mix: Easy-to-swallow capsules designed for seamless integration into your wellness regimen.
$19.99 Amazon Prime
Buy on Amazon
SaleBestseller No. 6
Energy & Mood Supplement – Boost Energy & Reduce Fatigue, Support Relaxation – 60 Capsules – Non-GMO, 3rd Party Tested – Innervis Nutrition
Energy & Mood Supplement – Boost Energy & Reduce Fatigue, Support Relaxation – 60 Capsules – Non-GMO, 3rd Party Tested – Innervis Nutrition
  • 5-in-1 Energy & Mood Support – One capsule combines Maca Root, Ashwagandha, Magnesium, Vitamin C, and Muira Puama to support balanced energy, calm focus, and mood stability.
  • High-Potency Maca & Ashwagandha – Adaptogens that help combat occasional fatigue, promote positive mood, and support hormonal balance for women and men.
  • Magnesium 200mg for Relaxation – Supports muscle function, nervous system health, and restful sleep. Ideal for adults seeking magnesium support.
  • Vitamin C Antioxidant Boost – Helps protect against oxidative stress, supports immune function, and aids recovery from daily activities.
  • Caffeine-Free Natural Vitality – Steady, balanced energy without jitters or crashes. Perfect for busy professionals, active adults, and those sensitive to caffeine.
$7.49 Amazon Prime
Buy on Amazon
Bestseller No. 7
Calmable Stress Relief Aid for Teens - Vegan - Pyridoxine B6, L-Theanine - Vitamin Dietary Supplement - 60 Capsules
Calmable Stress Relief Aid for Teens - Vegan - Pyridoxine B6, L-Theanine - Vitamin Dietary Supplement - 60 Capsules
  • SPECIALLY FORMULATED FOR TEENS: Don’t just take a generic stress relief supplement. These supplements are especially formulated for teenagers, to give you the stress relief that is right for your body. Enjoy capsules made specifically for youngsters.
  • POWERFUL RESEARCHED INGREDIENTS: These capsules are formulated with 20 mg vitamin B6, 680 mcg DFE folate, 1000 mcg vitamin B12, 500 mcg biotin, 15 mg zinc, 150 mg KSM-66 ashwagandha root extract, 100 mg L-theanine, 100 mg 5-Hydroxytryptophan (5-HTP), 50 mg lemon balm (aerial parts), 50 mg hops flower, 50 mg baikal skullcap root extract, 50 mg passionflower (aerial parts), and 10 mg black pepper fruit extract.
  • QUALITY YOU CAN TRUST: Our capsule supplements are made in the USA with domestic and global ingredients. They are produced with the utmost quality labs and ingredients, and manufactured in a top quality GMP approved facility. They are completely soy free, non-gmo, gluten free, vegan, and have naturally sourced ingredients.
  • MAX POTENCY AND ABSORPTION: Calmable gives you high-quality capsules with high potency and absorption. Our capsules are easy to swallow with 13 vitamins, minerals, and herbs, for the ultimate stress aid.
  • Our capsules are quite small, so that everyone can enjoy them. Whether you have a hard time taking capsules in general, or just have difficulties taking large pills, these capsules are specially designed to be smaller and easy to swallow. Our capsules are 1 inch long.
$17.99 Amazon Prime
Buy on Amazon
Bestseller No. 8
Habit Stress Relief Supplement (60 Capsules) - New Look, Supports Relaxation & Mood Balance, Vitamin B, Adaptogens, Lemon Balm, Calming, Vegan, Non-GMO (1 Pack)
Habit Stress Relief Supplement (60 Capsules) - New Look, Supports Relaxation & Mood Balance, Vitamin B, Adaptogens, Lemon Balm, Calming, Vegan, Non-GMO (1 Pack)
  • UNWIND YOUR MIND: Say yes to less stress. HABIT's Stress Relief supplement helps support a healthy stress response with science-backed nutrients and time-tested adaptogenic herbs*.
  • BIG ON BENEFITS: This nourishing formula supports calm, clarity and mood balance so you can stop grinding and start unwinding*.
  • WHAT’S INSIDE: A stress less blend of Vitamin B1, Vitamin B2, Niacinamide and Pantothenic Acid—plus adaptogens Ashwagandha, Bacopa and Lemon Balm.
  • WHY YOU’LL LOVE: These vegan, non-GMO capsules are free from gluten, synthetic colors and flavors.
  • GET INTO THE HABIT: HABIT helps create healthy HABITs that stick—even for commitment-phobes. HABIT’s range of targeted blends help you navigate and meet your health goals using language you can understand, for results you can feel.
$9.94 Amazon Prime
Buy on Amazon
Bestseller No. 9
5-HTP Formula for Stress Relief and relaxation support for Teens and Adults with 5-HTP, L-Theanine, Vitamin B6, Vitamin B12, Magnesium - Doctor Formulated - Magnesium Stearate Free - 60 capsules.
5-HTP Formula for Stress Relief and relaxation support for Teens and Adults with 5-HTP, L-Theanine, Vitamin B6, Vitamin B12, Magnesium - Doctor Formulated - Magnesium Stearate Free - 60 capsules.
  • For teenagers and adults suplements formula to help handle stress and relax: Magnesium 100mg, B6 10mg, B12 30mcg, L-Theanine 400mg, 5-HTP 100mg.
  • Calming with L-Theanine, a unique amino acid found in the green tea plant camelia sinesis. It supports balanced Cortisol during the most stressfull periods.
  • Support Serotonin with 5-HTP is extracted from the seeds of an African plant known as Griffonia simplicifolia.
  • Replenish Vitamin B6, vitamin B12 and magnesium during emotional or physical stress.
  • Helps to concentrate and focus throughout the day. Magnesium Stearate Free – AgeImmune is a Magnesium Stearate and Silica Free Brand. We do not use lubricants and flow agents in our encapsulation process.
$19.99 Amazon Prime
Buy on Amazon
Bestseller No. 10
DR. EMIL NUTRITION 200 MG 5-HTP Plus with SAM-e for Mood, Stress, and Sleep - 5HTP Supplement with Vitamin B6-120 Vegan Capsules, 60 Servings
DR. EMIL NUTRITION 200 MG 5-HTP Plus with SAM-e for Mood, Stress, and Sleep - 5HTP Supplement with Vitamin B6-120 Vegan Capsules, 60 Servings
  • Can Support Mood & Rest: We supplemented 200mg of pure 5-HTP with 20mg of SAMe to optimize 5-HTP conversion and support stress levels in the body.*
  • Vitamin B6 for Improved 5-HTP Conversion: Vitamin B6 has been shown to aid 5-HTP conversion. Even a slight B6 deficiency can greatly inhibit the efficacy of 5-HTP.
  • May Promote Calm and Relaxation: Dr. Emil’s 200 MG 5-HTP Plus formula is a natural way to promote a calm and relaxed mood by supporting 5-HTP conversion in the body.*
  • Doctor-Derived Formula: Dr. Emil Hodzovic has painstakingly formulated our 200 MG 5-HTP Plus supplement with the highest quality ingredients that are gluten-free, non-GMO, and manufactured in a cGMP facility to ensures that each product is 100% free of hype, hormones, and empty promises.
  • Made in the USA: All Dr. Emil products are made from all-natural vitamins, minerals & herbal extracts, without the use of harmful additives; non-GMO; free of gluten and all top 8 allergens. All products are manufactured in the USA in a GMP certified laboratory.
$37.60 Amazon Prime
Buy on Amazon

Important Aspects To Consider When Buying vitamin supplements for anxiety and depression

Even deciding on an insignificant purchase can make you feel like choosing between the red pill or the blue one. But is the headache really worth it? Online shopping was meant to make our experience simpler, easier and enjoyable. But in reality it is quite easy to get confused on the decision which one to buy?

This is where our efforts come in! This list of vitamin supplements for anxiety and depression will surely save you valuable time and effort. However another question remains, what makes our compilation the best? Or on what basis you should trust this vitamin supplements for anxiety and depression list.

Is it virtually possible to know every detail of a product for making a perfect purchase? The answer is definitely NO, it’s not! Then how do you make the correct decision while buying vitamin supplements for anxiety and depression? Well, the complexity of selecting a single product from a sea of them can be simplified taking into consideration a few key metrics regarding the product.

We feed thousands of data to our AI regarding these products through advanced algorithms. Based on the relevant data i.e. brand, features, specs, ratings and reviews and many others (which are discussed below) a list of best vitamin supplements for anxiety and depression has been prepared by the AI.

Brand Reputation:

Branded products might seem pricey but the point is they are charging those extra bucks for reliability. Unlike many other things, trust doesn’t come cheap. 8 out of 10 times you can trust a branded one.

Unique Features:

Enough and useful features make a product purchase worthy. This is the basic criteria to be followed.

Useful Specifications:

Matching the right specs according to your need is very important and we miss no important things.

Star Ratings:

Healthy ratings indicate a good product. Highest rated products rarely disappoint users. So, we pick the best rated units on our list.

Number of Reviews:

Higher number of reviews in the shortest period of time shows the product is accepted widely by a lot of customers. Customer feedback aka customer reviews are the most insightful source of judging a product’s merit. We take serious consideration into customer reviews and total numbers while choosing them.

Ratio of Positive Reviews Against Bad:

The final rating is an average of all ratings provided by users. But we can get a deeper look at the product’s performance if we analyze the ratings on each star level.

Ranking of the Seller:

Shows the reputation of the seller. Even if you choose the correct item, a bad seller can be a big hassle. So stare clear of them.

Product Ranking in Relevant Category:

These small little details are never left out of our consideration. This is what makes our selection even more confident and authentic.

Bang for the Buck:

Spending a fortune on vitamin supplements for anxiety and depression is not a wise thing to do. Our every selected item should provide you the best value for the money you spent.

Selling Growth Over the Product Lifetime:

A product might have thousands of reviews and good ratings, still can be a bad choice. Once hyped products can be an outdated choice now. So, a gradual positive growth of any product indicates its reliability.

Latest Models:

Every product is perfected with every new edition. Those little improvements, upgrades and adjustments come real handy in user experience. So, we keep in mind to choose the latest ones.

Product Availability:

Unavailable product is like a dead lion. Discontinued items are surely not recommended.

Rating By Features:

There is a special segment in amazon where the product is rated according to different relevant features. This one is mostly overlooked by everyone. But we keep a keen eye on this!

Overall Versatility:

A product needs to be versatile and user friendly. Our aim is to prepare a list of best vitamin supplements for anxiety and depression which will serve you in a wide range.

Amazon’s Preference:

Amazon’s choice can be a factor to consider. It creates a sense of reliability among customers. We value amazon’s choice and prepare all lists keeping this fact in mind.

Conclusion:

The article detailing the best vitamin supplements for anxiety and depression ends here. However, the best option for each person will vary depending on their individual needs and preferences. But here, the vitamin supplements for anxiety and depressions we have listed above, have great features and are highly rated by customers. So, I hope that it may have helped you finalize your decision to choose the best vitamin supplements for anxiety and depression for you.

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