An arthritis pain relief medication is a pharmaceutical drug used to treat the symptoms of arthritis. It can help to reduce pain and inflammation, as well as providing other benefits such as improving mobility and flexibility. Some of the renowned brands are Voltaren, Mobic, and Aleve.
Choosing the right arthritis pain relief medication is difficult as it depends on various factors such as the type of arthritis you have, your age, and other health conditions you may have. To make it easier to find the exact arthritis pain relief medication you’re looking for, we rounded up the best arthritis pain relief medications on Amazon, according to thousands of customer reviews.
Check out our favorite arthritis pain relief medications in the list below, and keep reading for our buying guide.
Our Editor’s Best Arthritis Pain Relief Medications Reviews
- One 1.7 oz/50 g tube of Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief
- Number 1 Doctor Recommended topical pain relief brand
- Clinically Proven to relieve arthritis pain, improve mobility and reduce stiffness, aches and pains to provide prescription strength arthritis pain relief
- An Alternative to Pills, Voltaren is a nonsteroidal anti-inflammatory gel that combines the benefits of an arthritis cream and gel for arthritis pain management
- Diclofenac Sodium Topical Gel Penetrates Deep to attack arthritis pain directly at the source of inflammation, treating arthritis pain
- Arthritis pain relief: Tylenol 8HR Arthritis Pain Caplets contain 650mg of acetaminophen; The extended release formula provides fast-acting, long-lasting relief for minor arthritis and joint pain in hands, wrists, knees, ankles, elbows, and feet
- Acetaminophen formula: Each Tylenol caplet contains 650 mg of acetaminophen in an extended-release formula specifically designed for arthritis pain relief; effectively reduces fever when needed
- Bi-layer technology: Tylenol Arthritis 8HR pain relief pills feature a dual-layer design—first layer releases fast-acting acetaminophen for quick relief, second layer extends pain relief for up to 8 hours; gentle on the stomach
- Safe & trusted: Aspirin-free, OTC pain relief pills are suitable for adults 18+; Tylenol is the #1 doctor recommended OTC brand for pain relief and fever reduction; safe when used as directed and gentle on the stomach
- Product details: Each bottle contains 100 extended-release caplets of acetaminophen 650mg; pain relief pills are aspirin-free and designed for effective, long-lasting arthritis pain relief
- Two 3.5 oz/100 g tubes of Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief- Easy flip cap that can be opened with your palm, fingers, or even with just one hand; packaging may vary
- Number 1 Doctor Recommended topical pain relief brand
- Clinically Proven to relieve arthritis pain, improve mobility and reduce stiffness, aches and pains to provide prescription strength arthritis pain relief
- An Alternative to Pills, Voltaren is a nonsteroidal anti-inflammatory gel that combines the benefits of an arthritis cream and gel for arthritis pain management*
- Voltaren Arthritis Pain Gel Penetrates Deep to attack arthritis pain directly at the source of inflammation, treating arthritis pain
- HEMP SEED OIL: our Hempvana Arthritis Pain Gel is enriched with ultra-moisturizing Hemp Seed Oil
- ULTRA-STRENGTH: to give you powerful relief from inflammation, swelling, and stiffness caused by arthritis
- TARGET THE PAIN: our Ultra-Strength Relief Gel targets pain right where it hurts, like your hands, fingers, and wrists. Plus other arthritic joints
- UNIQUE FORMULA: made with 100% pure cold-pressed hemp seed oil and FDA-listed pain-fighting menthol for active pain relief
- NON-GREASY: Unlike other ointments that leave a greasy mess, Hempvana is non-greasy and absorbs quickly
- One 5.3 oz/150 g tube of Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief- Easy flip cap that can be opened with your palm, fingers, or even with just one hand; packaging may vary
- Number 1 Doctor Recommended topical pain relief brand
- Clinically Proven to relieve arthritis pain, improve mobility and reduce stiffness, aches and pains to provide prescription strength arthritis pain relief
- An Alternative to Pills, Voltaren is a nonsteroidal anti-inflammatory gel that combines the benefits of an arthritis cream and gel for arthritis pain management
- Voltaren Arthritis Pain Gel Penetrates Deep to attack arthritis pain directly at the source of inflammation, treating arthritis pain
- BC Powder Arthritis Pain Reliever temporarily provides arthritis pain relief and other body related aches and pains
- Powerful, dual-action powder pain relief formula contains a higher dose of the ingredients in BC Original Strength formula to help stop minor arthritis pain fast
- Pain relief powder that dissolves faster than pills and contains Aspirin, 1,000 mg (NSAID), and Caffeine, 65 mg; no prescription needed
- Convenient, fast-acting, single-serving dissolve packs to get arthritis relief on-the-go BC powder packets are an OTC medication & treatment that are FSA- & HSA-eligible in the U.S
- BC powder packets are an OTC medication & treatment that are FSA- & HSA-eligible in the U.S.
- NSAID-FREE ARTHRITIS RELIEF: Experience relief from arthritis pain without the use of NSAIDs. Arnicare Arthritis Pain Relief Tablets are formulated with Arnica and other pure active ingredients to provide relief for minor joint pain and stiffness.* For added relief, pair with Arnicare Arthritis Cream.
- MELT AWAY JOINT PAIN: Designed to be taken at the first signs of a flare, Arnicare Arthritis Pain Relief Tablets melt in your mouth without the need for food or water. Simply let the tablets dissolve in your mouth to experience relief from the minor aches and pain of arthritis.
- HELP YOUR BODY THE NATURAL WAY: Arnicare Arthritis Pain Relief Tablets have no known interactions with other medications or supplements and no contraindications. Gluten-free and no artificial sweeteners, flavors, colors, or preservatives.
- A TRUSTED BRAND: With over 90 years of expertise, Boiron is the Arnica expert whose Arnicare line is the #1 homeopathic Arnica pain relief brand. Boiron medicines are made in FDA-inspected facilities and meet the highest standards of cGMP and HPUS for purity and quality.
- BUY WITH HSA/FSA: Boiron Arnicare pain relievers are HSA & FSA eligible in the U.S.
- Up to 12-Hours of Uninterrupted Pain Relief: Aleve Pain Reliever & Fever Reducer Gelcaps provide long-lasting arthritis pain relief, as well as relief from muscular aches, backache, menstrual cramps, headache, toothache, and the common cold
- Easy Open Arthritis Cap: Specially designed arthritis bottle features an easy to open, cushionedcovered cap and contoured bottle for better control when your arthritis acts up. Package is not child-resistant
- Fever Reducer: Temporarily reduces fever for adults and children aged 12 and up
- Targeted Pain Relief: naproxen sodium relieves minor pain from arthritis
- Effective Pain Reliever: In a study, proven as effective and longer lasting than a common Rx pain reliever. Ask a doctor if Aleve is right for you
- DUAL ACTION: Scientifically formulated with Arnica Montana and Harpagophytum (Devil’s Claw) for dual action pain relief. Addresses minor arthritis pain at its source and is suitable for use on all joints.
- TOPICAL PAIN RELIEF: The non-greasy light, silky texture quickly absorbs into skin is ideal for sudden flare-ups and soreness.
- PLANT-BASED ACTIVE INGREDIENT: Arnica Montana and Harpagophytum are natural pain relievers. No camphor, menthol, or other ingredients that cause burning or stinging and is paraben-free.
- ASPIRIN FOR DOGS: Nutri-Vet Aspirin for Dogs is formulated to keep your furry friend happy and active; Specifically designed for medium to large breeds, these 300 mg tablets provide temporary pain relief for dogs and reduce inflammation
- ARTHRITIS AND JOINT CARE: Unleash the true power of dog pain relief; Our aspirin is specially formulated to ease arthritis and joint pain; Embrace a lifestyle of comfort and agility with dog arthritis pain relief; Your pet's wellness is our priority
- GREAT TASTE: Our canine aspirin tablets come with an irresistible liver flavor that dogs love; Our tablets combine the benefits of dog pain medicine with a taste that will make medication time a delightful experience for both you and your pet
- VETERINARIAN FORMULATED: Crafted with care by professionals, our dog aspirin is formulated by experienced veterinarians; Made with your pet in mind, our dog pain reliever ensures quality and safety for your dog
- MADE IN THE USA: Proudly made in the USA with premium globally sourced ingredients, our tablets carry the National Animal Supplement (NASC) quality seal; We offer dog pain relief, dog supplements, and joint pain relief that symbolize quality and care
Best Arthritis Pain Relief Medications Buying Guide
Before choosing the best arthritis pain relief medications you should consider following options:
1. Aspirin and Other Nonsteroidal Anti-inflammatory Drugs (NSAIDs): NSAIDs reduce inflammation by inhibiting the production of prostaglandins, chemicals your body makes to cause inflammation.
These include aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib (Celebrex), and many others.
Aspirin is often used for its cardioprotective effects and to reduce the risk of heart attacks.
The most common side effect of NSAIDs is upset stomach and/or gastrointestinal bleeding.
NSAIDs are often used for the treatment of mild to moderate arthritis pain. They are also used for the treatment of aches and pains associated with other disorders such as muscle strains and back pain.
NSAIDs are not recommended for long-term use because they can cause kidney damage and liver damage when taken for a prolonged period of time.
2. Corticosteroids: Corticosteroids reduce inflammation by suppressing the immune system.
They are not recommended for long-term use because they can cause serious side effects, including high blood pressure and increased susceptibility to infection.
Corticosteroids are often used for the treatment of severe arthritis pain. They are also used for the treatment of other disorders where inflammation is a cause of significant pain, such as Crohn’s disease, ulcerative colitis, lupus, and others.
3. Nonsteroidal Anti-inflammatory Agents That Block COX-2: Celecoxib (Celebrex) and others belong to this group. These are used for the treatment of mild to moderate arthritis pain. The most common side effects are nausea, upset stomach, and gastrointestinal bleeding.
4. Oral Steroidal Drugs: Cortisone is one example of an oral steroid. These are used for the treatment of severe arthritis pain.
Side effects include adrenal suppression, osteoporosis, muscle weakness and thinning, glaucoma, and others.
5. Opioid Drugs: Opioids block the transmission of pain signals in the nervous system. They include hydrocodone ( Vicodin, Lortab), oxycodone (Percocet), morphine (Kadian), codeine, fentanyl (Duragesic), and others.
Common side effects of opioids include nausea, constipation, drowsiness, and addiction.
6. Topical Drugs: These reduce inflammation by cooling, drying, and reducing swelling.
Common side effects include skin irritation and burning sensation. These are often used for the treatment of back pain and other musculoskeletal disorders.
7. Corticosteroid Injections: Corticosteroid injections reduce inflammation by suppressing the immune system. These are often used for the treatment of back pain and other musculoskeletal disorders.
Side effects include infection, disc swelling, and worsening of back pain.
8. Opioid Injections: These reduce pain signals by blocking the transmission of pain signals in the nervous system. Common side effects include nausea, constipation, drowsiness, and addiction.
9. Opioid Patches: These reduce pain signals by blocking the transmission of pain signals in the nervous system. Common side effects include nausea, constipation, drowsiness, and addiction.
10. Opioid Patches with Combination NSAID and Opioid: One example of this combination is triclofed t gel. Common side
What else you should know about arthritis pain relief medications
1. What are the best arthritis pain relief medications?
There is no one-size-fits-all answer to this question, as the best arthritis pain relief medication for a particular individual may vary depending on the individual’s specific situation and health condition. However, some common arthritis pain relief medications include over-the-counter pain relievers such as acetaminophen or ibuprofen, prescription NSAIDs (non-steroidal anti-inflammatory drugs), DMARDs (disease-modifying anti-rheumatic drugs), and biologic agents.
2. What are the side effects of arthritis pain relief medications?
The side effects of arthritis pain relief medications can vary depending on the medication. Some common side effects include stomach pain, diarrhea, constipation, headache, and dizziness.
3. How do arthritis pain relief medications work?
The most common arthritis pain relief medications are anti-inflammatory drugs, which work by reducing inflammation in the joints.
4. What are the risks of taking arthritis pain relief medications?
There are a number of risks associated with taking arthritis pain relief medications, including gastrointestinal bleeding, ulcers, kidney damage, and liver damage.
5. Are there any natural arthritis pain relief medications?
There are a number of natural arthritis pain relief medications available. Some of these include omega-3 supplements, turmeric, ginger, and garlic.
Conclusion
On the market, there are numerous best arthritis pain relief medications. Hopefully, the list of the top ten best arthritis pain relief medications will save you time researching and deciding on the best one for you.