• Skip to primary navigation
  • Skip to main content
  • Skip to primary sidebar
  • Skip to footer
etcly

Etcly

Everything That Matters

  • Lifestyle
  • Health
  • Food
  • Celebrity News
  • Pet
  • Contact
You are here: Home / Reviews / Best Arthritis Pain Relief Medications

Best Arthritis Pain Relief Medications

An arthritis pain relief medication is a pharmaceutical drug used to treat the symptoms of arthritis. It can help to reduce pain and inflammation, as well as providing other benefits such as improving mobility and flexibility. Some of the renowned brands are Voltaren, Mobic, and Aleve.

Choosing the right arthritis pain relief medication is difficult as it depends on various factors such as the type of arthritis you have, your age, and other health conditions you may have. To make it easier to find the exact arthritis pain relief medication you’re looking for, we rounded up the best arthritis pain relief medications on Amazon, according to thousands of customer reviews.

Check out our favorite arthritis pain relief medications in the list below, and keep reading for our buying guide.

# Preview Product Price
1 Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac, No Prescription Needed - 1.7 oz/50 g Tube Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac, No... $10.98Amazon Prime Buy on Amazon
2 Tylenol 8HR Arthritis Pain Relief Caplets, 650 mg Acetaminophen Pain Relief Pills for Minor Arthritis Pain & Joint Pain, Fever Reducer, Oral Pain Reliever for Joint Pain; 100 ct.; Pack of 8 Tylenol 8HR Arthritis Pain Relief Caplets, 650 mg Acetaminophen Pain Relief Pills for Minor... $12.47Amazon Prime Buy on Amazon
3 Hempvana Arthritis Pain Relief Gel, Ultra-Strength for Arthritis in Muscles & Joints. Enriched with Hemp Seed Oil, AS-SEEN-ON-TV. Non-Greasy. Targeted Long-Lasting Arthritis Relief. Works Fast, 4 Oz. Hempvana Arthritis Pain Relief Gel, Ultra-Strength for Arthritis in Muscles & Joints. Enriched with... $18.88Amazon Prime Buy on Amazon
4 Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac - NEW Easy Open Cap - 100 g x 2 Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac - NEW Easy... $32.99Amazon Prime Buy on Amazon
5 Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac - NEW Easy Open Cap - 150 g Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac - NEW Easy... $21.00Amazon Prime Buy on Amazon
6 Boiron Arnicare Arthritis Tablets for Arthritis Pain Relief, Joint Soreness, and Rheumatic Pain - 60 Count Boiron Arnicare Arthritis Tablets for Arthritis Pain Relief, Joint Soreness, and Rheumatic Pain - 60... $10.49Amazon Prime Buy on Amazon
7 Boiron Arnicare Arthritis Cream for Pain Relief of Knees, Hands, Wrists, Elbows, Joints & Muscles – Quickly Absorbed & Fragrance-Free – 2.5 oz Boiron Arnicare Arthritis Cream for Pain Relief of Knees, Hands, Wrists, Elbows, Joints & Muscles... $14.99Amazon Prime Buy on Amazon
8 MediNatura T-Relief Pet Arthritis Pain Relief Arnica +12 Powerful Natural Medicines Help Reduce Hip & Joint Pain, Soreness & Stiffness - Fast-Acting Drops for Dog & Cat - 1.69 oz MediNatura T-Relief Pet Arthritis Pain Relief Arnica +12 Powerful Natural Medicines Help Reduce Hip... $18.99Amazon Prime Buy on Amazon
9 Aleve Gelcaps with Easy Open Arthritis Cap, Naproxen Sodium, Medication for Arthritis Pain, 160 Count Aleve Gelcaps with Easy Open Arthritis Cap, Naproxen Sodium, Medication for Arthritis Pain, 160... $25.17Amazon Prime Buy on Amazon
10 Australian Dream Arthritis Pain Relief Cream - Soothing & Non-Greasy - Powerful Topical Arthritis Pain Relief - Good for Muscle Aches or Joints - 2 oz Jar Australian Dream Arthritis Pain Relief Cream - Soothing & Non-Greasy - Powerful Topical Arthritis... $16.99Amazon Prime Buy on Amazon

Our Editor’s Best Arthritis Pain Relief Medications Reviews

Bestseller No. 1
Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac, No Prescription Needed - 1.7 oz/50 g Tube
Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac, No Prescription Needed - 1.7 oz/50 g Tube
  • One 1.7 oz/50 g tube of Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief
  • Number 1 Doctor Recommended topical pain relief brand
  • Clinically Proven to relieve arthritis pain, improve mobility and reduce stiffness, aches and pains to provide prescription strength arthritis pain relief
  • An Alternative to Pills, Voltaren is a nonsteroidal anti-inflammatory gel that combines the benefits of an arthritis cream and gel for arthritis pain management
  • Diclofenac Sodium Topical Gel Penetrates Deep to attack arthritis pain directly at the source of inflammation, treating arthritis pain
$10.98 Amazon Prime
Buy on Amazon
Bestseller No. 2
Tylenol 8HR Arthritis Pain Relief Caplets, 650 mg Acetaminophen Pain Relief Pills for Minor Arthritis Pain & Joint Pain, Fever Reducer, Oral Pain Reliever for Joint Pain; 100 ct.; Pack of 8
Tylenol 8HR Arthritis Pain Relief Caplets, 650 mg Acetaminophen Pain Relief Pills for Minor Arthritis Pain & Joint Pain, Fever Reducer, Oral Pain Reliever for Joint Pain; 100 ct.; Pack of 8
  • ARTHRITIS PAIN RELIEF: Tylenol 8HR Arthritis Pain Extended-Release Caplets with 650 mg acetaminophen caplets provides fast-acting, temporary relief of minor arthritis and joint pain targeted in the hands, wrists, knees, ankles, elbows, and feet.
  • ACETAMINOPHEN FORMULA: Each Tylenol 8HR Arthritis Pain relief pill contains 650 mg of acetaminophen in each caplet; For effective pain relief of minor arthritis and joint pains; Effective fever reducer.
  • Tylenol 8HR ARTHRITIS PAIN Relief PILLS: Includes 100 caplets; use 650 mg acetaminophen caplets to help provide Arthritis pain relief; The first layer of the bi-layer pill acts fast to relieve pain, and the second lasts up to 8 hours.
  • HOW To USE: Adults ages 18+, take two arthritis pain relief caplets every 8 hours while symptoms last; Do not exceed 6 capsule in 24 hours unless directed by a doctor.
  • INCLUDES: Pack of 1, 100 Tylenol 8HR Arthritis Pain Extended-Release pain relief caplets; #1 doctor recommended brand for pain relief and fever reduction; When used as directed Tylenol 8HR Arthritis Pain Relief offers an excellent safety profile.
$12.47 Amazon Prime
Buy on Amazon
SaleBestseller No. 3
Hempvana Arthritis Pain Relief Gel, Ultra-Strength for Arthritis in Muscles & Joints. Enriched with Hemp Seed Oil, AS-SEEN-ON-TV. Non-Greasy. Targeted Long-Lasting Arthritis Relief. Works Fast, 4 Oz.
Hempvana Arthritis Pain Relief Gel, Ultra-Strength for Arthritis in Muscles & Joints. Enriched with Hemp Seed Oil, AS-SEEN-ON-TV. Non-Greasy. Targeted Long-Lasting Arthritis Relief. Works Fast, 4 Oz.
  • HEMP SEED OIL: our Hempvana Arthritis Pain Gel is enriched with ultra-moisturizing Hemp Seed Oil
  • ULTRA-STRENGTH: to give you powerful relief from inflammation, swelling, and stiffness caused by arthritis
  • TARGET THE PAIN: our Ultra-Strength Relief Gel targets pain right where it hurts, like your hands, fingers, and wrists. Plus other arthritic joints
  • UNIQUE FORMULA: made with 100% pure cold-pressed hemp seed oil and FDA-listed pain-fighting menthol for active pain relief
  • NON-GREASY: Unlike other ointments that leave a greasy mess, Hempvana is non-greasy and absorbs quickly
$18.88 Amazon Prime
Buy on Amazon
Bestseller No. 4
Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac - NEW Easy Open Cap - 100 g x 2
Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac - NEW Easy Open Cap - 100 g x 2
  • Two 3.5 oz/100 g tubes of Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief- Easy flip cap that can be opened with your palm, fingers, or even with just one hand; packaging may vary
  • Number 1 Doctor Recommended topical pain relief brand
  • Clinically Proven to relieve arthritis pain, improve mobility and reduce stiffness, aches and pains to provide prescription strength arthritis pain relief
  • An Alternative to Pills, Voltaren is a nonsteroidal anti-inflammatory gel that combines the benefits of an arthritis cream and gel for arthritis pain management*
  • Voltaren Arthritis Pain Gel Penetrates Deep to attack arthritis pain directly at the source of inflammation, treating arthritis pain
$32.99 Amazon Prime
Buy on Amazon
SaleBestseller No. 5
Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac - NEW Easy Open Cap - 150 g
Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac - NEW Easy Open Cap - 150 g
  • One 5.3 oz/150 g tube of Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief- Easy flip cap that can be opened with your palm, fingers, or even with just one hand; packaging may vary
  • Number 1 Doctor Recommended topical pain relief brand
  • Clinically Proven to relieve arthritis pain, improve mobility and reduce stiffness, aches and pains to provide prescription strength arthritis pain relief
  • An Alternative to Pills, Voltaren is a nonsteroidal anti-inflammatory gel that combines the benefits of an arthritis cream and gel for arthritis pain management
  • Voltaren Arthritis Pain Gel Penetrates Deep to attack arthritis pain directly at the source of inflammation, treating arthritis pain
$21.00 Amazon Prime
Buy on Amazon
SaleBestseller No. 6
Boiron Arnicare Arthritis Tablets for Arthritis Pain Relief, Joint Soreness, and Rheumatic Pain - 60 Count
Boiron Arnicare Arthritis Tablets for Arthritis Pain Relief, Joint Soreness, and Rheumatic Pain - 60 Count
  • Before pain gets in your way, treat it naturally at the first sign with Arnicare and feel better faster. Arnicare Arthritis Tablets are the perfect solution for those suffering from arthritis pain, specifically from stiff and swollen joints and flare-ups caused by changes in weather. Arnicare Arthritis comes in a quick-dissolving tablet form.
  • Arnica montana (or Mountain daisy) has been used for centuries as a natural pain reliever, and today, it’s one of the most popular homeopathic medicines in the world. Arnica is trusted by professional athletes to soothe sore muscles, by prominent cosmetic surgeons to relieve post-procedure pain, and by savvy moms to treat playground bumps and bruises.
  • Arnicare Arthritis's natural active ingredients help to relieve pain from stiff and inflamed joints, minor aches and pains associated with arthritis, as well as wrist, finger joint and rheumatic pain.
  • Arnicare Arthritis Tablets work naturally with your body, and there’s no risk of overdose, no contraindications, no known drug interactions, and a very low risk of side effects when used as directed.
  • At Boiron, we believe there’s more than one way to feel better. Since 1932, the Boiron family has been committed to providing quality medicines. As world leader in homeopathy, our passion is your health. Our promise is your satisfaction.
$10.49 Amazon Prime
Buy on Amazon
SaleBestseller No. 7
Boiron Arnicare Arthritis Cream for Pain Relief of Knees, Hands, Wrists, Elbows, Joints & Muscles – Quickly Absorbed & Fragrance-Free – 2.5 oz
Boiron Arnicare Arthritis Cream for Pain Relief of Knees, Hands, Wrists, Elbows, Joints & Muscles – Quickly Absorbed & Fragrance-Free – 2.5 oz
  • DUAL ACTION: Scientifically formulated with Arnica Montana and Harpagophytum (Devil’s Claw) for dual action pain relief. Addresses minor arthritis pain at its source and is suitable for use on all joints.
  • TOPICAL PAIN RELIEF: The non-greasy light, silky texture quickly absorbs into skin is ideal for sudden flare-ups and soreness.
  • PLANT-BASED ACTIVE INGREDIENT: Arnica Montana and Harpagophytum are natural pain relievers. No camphor, menthol, or other ingredients that cause burning or stinging and is paraben-free.
$14.99 Amazon Prime
Buy on Amazon
Bestseller No. 8
MediNatura T-Relief Pet Arthritis Pain Relief Arnica +12 Powerful Natural Medicines Help Reduce Hip & Joint Pain, Soreness & Stiffness - Fast-Acting Drops for Dog & Cat - 1.69 oz
MediNatura T-Relief Pet Arthritis Pain Relief Arnica +12 Powerful Natural Medicines Help Reduce Hip & Joint Pain, Soreness & Stiffness - Fast-Acting Drops for Dog & Cat - 1.69 oz
  • SOOTHE WHOLE BODY HOMEOPATHY - Manage your besties pain naturally with the power of Arnica plus 12 plants and tissue extracts known to alleviate minor arthritis pain and support joint mobility, flexibility, and lasting relief.
  • PLANT-BASED CARE FOR PETS TO THRIVE - Lasting relief of aches and pains helps your furry friend get back to doing what they love; gentle formula can be used with your pet's daily glucosamine supplements, vitamins or medication without known interaction.
  • BOOST THE BODY'S DEFENSES - Homeopathic formulas address symptoms with a micro dose of an active ingredient to stimulate the body’s own defenses; we combine multiple potent actives in multiple concentrations for greater relief of more symptoms.
  • VETS KNOW BEST - Formulated by a holistic veterinarian, quick-dissolve drops can be easily mixed with water or food instead of disguising medicine in treats and chews that pets spit out; dosages provided for dogs, cats, and horses from newborn to adults.
  • FEEL GOOD MEDICINES FROM THE EARTH - Natural reliever without risk, a safe non-narcotic alternative with no known interactions or side effects; doesn't just mask pain but goes to its source by supporting their own self-healing mechanisms.
$18.99 Amazon Prime
Buy on Amazon
Bestseller No. 9
Aleve Gelcaps with Easy Open Arthritis Cap, Naproxen Sodium, Medication for Arthritis Pain, 160 Count
Aleve Gelcaps with Easy Open Arthritis Cap, Naproxen Sodium, Medication for Arthritis Pain, 160 Count
  • Up to 12-Hours of Uninterrupted Pain Relief: Aleve Pain Reliever & Fever Reducer Gelcaps provide long-lasting arthritis pain relief, as well as relief from muscular aches, backache, menstrual cramps, headache, toothache, and the common cold
  • Easy Open Arthritis Cap: Specially designed arthritis bottle features an easy to open, cushionedcovered cap and contoured bottle for better control when your arthritis acts up. Package is not child-resistant
  • Fever Reducer: Temporarily reduces fever for adults and children aged 12 and up
  • Targeted Pain Relief: naproxen sodium relieves minor pain from arthritis
  • Effective Pain Reliever: In a study, proven as effective and longer lasting than a common Rx pain reliever. Ask a doctor if Aleve is right for you
$25.17 Amazon Prime
Buy on Amazon
Bestseller No. 10
Australian Dream Arthritis Pain Relief Cream - Soothing & Non-Greasy - Powerful Topical Arthritis Pain Relief - Good for Muscle Aches or Joints - 2 oz Jar
Australian Dream Arthritis Pain Relief Cream - Soothing & Non-Greasy - Powerful Topical Arthritis Pain Relief - Good for Muscle Aches or Joints - 2 oz Jar
  • Soothing Pain Relief: Our Australian Dream Arthritis Pain Relief Cream is easily absorbed, providing a powerful, effective formula for muscle and joint pains
  • Powerful, Economical Relief: Our cream provides a powerful solution to your arthritis pain, and it doesn't take much to do the job
  • Odorless & Non-Greasy: Our arthritis pain relief cream is non-greasy, odorless, and doesn't burn, making it perfect for sore muscles and painful joints
  • High-Quality Formula: With histamine dihydrochloride, this pain cream provides temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backache, strains, sprains, and bruises
  • Moving is Living: Australian Dream is dedicated to relieving pain and promoting comfort; this dedication is why we’re America’s first premium topical analgesic pain reliever
$16.99 Amazon Prime
Buy on Amazon

Best Arthritis Pain Relief Medications Buying Guide

Before choosing the best arthritis pain relief medications you should consider following options:

1. Aspirin and Other Nonsteroidal Anti-inflammatory Drugs (NSAIDs): NSAIDs reduce inflammation by inhibiting the production of prostaglandins, chemicals your body makes to cause inflammation.

These include aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib (Celebrex), and many others.

Aspirin is often used for its cardioprotective effects and to reduce the risk of heart attacks.

The most common side effect of NSAIDs is upset stomach and/or gastrointestinal bleeding.

NSAIDs are often used for the treatment of mild to moderate arthritis pain. They are also used for the treatment of aches and pains associated with other disorders such as muscle strains and back pain.

NSAIDs are not recommended for long-term use because they can cause kidney damage and liver damage when taken for a prolonged period of time.

2. Corticosteroids: Corticosteroids reduce inflammation by suppressing the immune system.

They are not recommended for long-term use because they can cause serious side effects, including high blood pressure and increased susceptibility to infection.

Corticosteroids are often used for the treatment of severe arthritis pain. They are also used for the treatment of other disorders where inflammation is a cause of significant pain, such as Crohn’s disease, ulcerative colitis, lupus, and others.

3. Nonsteroidal Anti-inflammatory Agents That Block COX-2: Celecoxib (Celebrex) and others belong to this group. These are used for the treatment of mild to moderate arthritis pain. The most common side effects are nausea, upset stomach, and gastrointestinal bleeding.

4. Oral Steroidal Drugs: Cortisone is one example of an oral steroid. These are used for the treatment of severe arthritis pain.

Side effects include adrenal suppression, osteoporosis, muscle weakness and thinning, glaucoma, and others.

5. Opioid Drugs: Opioids block the transmission of pain signals in the nervous system. They include hydrocodone ( Vicodin, Lortab), oxycodone (Percocet), morphine (Kadian), codeine, fentanyl (Duragesic), and others.

Common side effects of opioids include nausea, constipation, drowsiness, and addiction.

6. Topical Drugs: These reduce inflammation by cooling, drying, and reducing swelling.

Common side effects include skin irritation and burning sensation. These are often used for the treatment of back pain and other musculoskeletal disorders.

7. Corticosteroid Injections: Corticosteroid injections reduce inflammation by suppressing the immune system. These are often used for the treatment of back pain and other musculoskeletal disorders.

Side effects include infection, disc swelling, and worsening of back pain.

8. Opioid Injections: These reduce pain signals by blocking the transmission of pain signals in the nervous system. Common side effects include nausea, constipation, drowsiness, and addiction.

9. Opioid Patches: These reduce pain signals by blocking the transmission of pain signals in the nervous system. Common side effects include nausea, constipation, drowsiness, and addiction.

10. Opioid Patches with Combination NSAID and Opioid: One example of this combination is triclofed t gel. Common side

What else you should know about arthritis pain relief medications

1. What are the best arthritis pain relief medications?

There is no one-size-fits-all answer to this question, as the best arthritis pain relief medication for a particular individual may vary depending on the individual’s specific situation and health condition. However, some common arthritis pain relief medications include over-the-counter pain relievers such as acetaminophen or ibuprofen, prescription NSAIDs (non-steroidal anti-inflammatory drugs), DMARDs (disease-modifying anti-rheumatic drugs), and biologic agents.

2. What are the side effects of arthritis pain relief medications?

The side effects of arthritis pain relief medications can vary depending on the medication. Some common side effects include stomach pain, diarrhea, constipation, headache, and dizziness.

3. How do arthritis pain relief medications work?

The most common arthritis pain relief medications are anti-inflammatory drugs, which work by reducing inflammation in the joints.

4. What are the risks of taking arthritis pain relief medications?

There are a number of risks associated with taking arthritis pain relief medications, including gastrointestinal bleeding, ulcers, kidney damage, and liver damage.

5. Are there any natural arthritis pain relief medications?

There are a number of natural arthritis pain relief medications available. Some of these include omega-3 supplements, turmeric, ginger, and garlic.

Conclusion

On the market, there are numerous best arthritis pain relief medications. Hopefully, the list of the top ten best arthritis pain relief medications will save you time researching and deciding on the best one for you.

Primary Sidebar

Related Posts

  1. Best Visual Impairment Writing Aids
  2. Best First Aid Ointments
  3. Best Jock Itch Treatments
  4. Best Hot Water Bottles
  5. Best Nail Fungus Treatments
  6. Best Lice Treatment Sprays
  7. Best Foot Odor Control Powders
  8. Best Foot Odor Control Sprays
  9. Best Insect Bite Treatments
  10. Best Poison Ivy Treatments

Recent Posts

  • Best 16-inch Brushless Cordless Chainsaws
  • Best 10 Cup Rice Cookers
  • Best Smart Watch For Men
  • Best Kitchen Knife Set
  • Best Holiday Gift Baskets
  • Best Bpa Free Electric Kettle
  • Best Family Gift Baskets For Christmas
  • Best Scratchboard Art Materials
  • Best Sculpture Molding Casting Products
  • Best Sculpture Release Agents
  • Best Sculpture Modeling Tools
  • Best Papier Mache Supplies
  • Best Paper Craft Tools
  • Best Card Making Kits
  • Best Leathercraft Lacing Needles
  • Best Sewing Sequin Trim

Follow Us

  • Facebook
  • Twitter

Footer

etcly

ETCLY.com is an Internet Web magazine that covers almost every topic you can think of. Technology seems like a wire that runs through our lives.

Learn More →
  • Facebook
  • Twitter

Browse

  • Aquarium
  • Bags & Luggage
  • Bathroom
  • Best Tools
  • Bins
  • Brands
  • Business
  • Camera
  • Cat
  • Celebrity News
  • Cleaner
  • Computer
  • Dog
  • Electronics
  • Fashion
  • Food
  • Gaming
  • Garden
  • Health
  • Horse
  • How To Clean
  • Ice
  • Infographic
  • Jewelry
  • Kitchen Appliances
  • Kitchen Knives
  • LED
  • Lifestyle
  • Light
  • Money
  • Music
  • Pet
  • Popular
  • Shoes & Slippers
  • Sports
  • Terrarium
  • Vacuum Cleaners
  • Water
  • About
  • Contact
  • Privacy Policy

Etcly.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to amazon.com. Amazon and the Amazon logo are trademarks of Amazon.com, Inc. or its affiliates.

Copyright © 2025 • etcly.com • All Rights Reserved