If your dog is constantly scratching and biting at himself, he may have a flea infestation.
To help ward off fleas, you can use flea drops on your dog, which are applied directly to the skin in between your dog’s shoulder blades. However, flea drops may not work as well as you’d expect, depending on the type you buy.
Here are the best dog flea drops.
Best Dog Flea Drops: Editor Recommended
Our Editor’s Best Dog Flea Drops Reviews
- Keep your dog protected from fleas & ticks all month long with FRONTLINE Plus for Dogs a fast-acting, waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease
- Break the flea life cycle with FRONTLINE Plus, specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control
- Trusted by pet owners for over 20 years, FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply with one monthly dose providing protection from fleas & ticks for a full 30 days
- FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over, so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products
- Treat all dogs or cats in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations
- KILLS FLEAS & TICKS: Kills fleas, flea eggs, deer ticks, and brown dog ticks on contact – it is important for your pup to have a flea and tick prevention treatment all year round!
- PREVENTS RE-INFESTATION: This topical formula prevents re-infestation by breaking the flea life cycle for up to 30 days.
- FAST ACTING FULL BODY PROTECTION: Active ingredients spread across the skin using your dog’s natural oil to quickly travel across the coat for full body protection from head to tail.
- 6 MONTHLY FLEA & TICK TREATMENTS: Contains 6 single dose tubes (1 tube per monthly application) for non-stop protection for up to 6 months. Apply at the base of your dog’s back between the shoulder blades each month.
- LARGE DOG FLEA TREATMENT: Specifically designed for small dogs up to 15 pounds, our flea medicine for dogs applies directly to the skin, effectively killing and repelling fleas and ticks for a full month
- CERTIFIED NATURAL: Give your dog the best with our blend of natural ingredients like clove, thyme, and cinnamon oil; our carefully selected ingredients make this natural tick repellent for dogs a safe and effective alternative to harsh chemicals
- EASY APPLICATION: This flea repellent for dogs comes with an applicator, making application a breeze; simply squeeze on and let the formula do its work; say goodbye to messy flea medicine for dogs and hello to easy tick and flea prevention for dogs
- VETERINARIAN FORMULATED: Our flea and tick treatment for dogs is the result of years of research and testing by our top vets; we've combined the latest scientific advancements with natural ingredients to create a formula that is safe and highly effective
- MADE IN THE USA: Our flea medicine for dogs is made in the USA with high-quality domestic and internationally sourced ingredients, ensuring that you are providing the best care possible for you beloved furry friend
- K9 Advantix II Large Dog 30-day treatment & prevention protects dogs 21-55 lbs. from fleas, ticks, mosquitoes, biting flies and lice
- Kills fleas within 12 hours of application
- Vet-recommended formula kills & repels on contact so fleas don’t have to bite your dog to die
- Easy-to-apply topical treatment is fragrance-free and waterproof after 24 hours
- No prescription needed
- K9 Advantix II Extra Large Dog 30-day treatment & prevention protects dogs over 55 lbs. from fleas, ticks, mosquitoes, biting flies and lice
- Kills fleas within 12 hours of application
- Vet-recommended formula kills & repels on contact so fleas don’t have to bite your dog to die
- Easy-to-apply topical treatment is fragrance-free and waterproof after 24 hours
- No prescription needed
- K9 Advantix II Medium Dog 30-day treatment & prevention protects dogs 11-20 lbs. from fleas, ticks, mosquitoes, biting flies and lice
- Kills fleas within 12 hours of application
- Vet-recommended formula kills & repels on contact so fleas don’t have to bite your dog to die
- Easy-to-apply topical treatment is fragrance-free and waterproof after 24 hours
- No prescription needed
- DOG FLEA AND TICK CONTROL: PetArmor topical flea and tick treatment kills adult fleas, ticks and chewing lice. Backed by the PetArmor Protection Guarantee.
- VET QUALITY FORMULA: Dog flea treatment contains the active ingredient fipronil.
- FAST-ACTING FLEA TREATMENT: PetArmor flea treatment for dogs can help you stop an existing flea or tick infestation.
- FLEA AND TICK PREVENTION: PetArmor for dogs helps you protect your furry family member from brown dog ticks, American dog ticks, lone star ticks, and deer ticks (which may transmit Lyme disease).
- INCLUDES: Three (3) topical application tubes for a 3 month supply of dog and flea and tick control. For best results, apply flea & tick treatment for dogs directly to dry skin on your dog's back-between the shoulder blades-on a monthly basis.
- 【Gentle Flea & Tick Relief – Plant-Based Protection】Worried about fleas, ticks, or mosquitoes bothering your pet? Our Natural Flea & Tick Support Drops for Pets use plant-based extracts to help your dog or cat stay comfortable through seasonal challenges, while also supporting skin health. Free from harsh chemicals and safe for daily use, these natural flea treatment drops help your pet stay active and itch-free. Because we know they deserve comfort every day—this oral liquid flea drop was made with their well-being in mind.
- 【Complete Wellness with Natural Nutrients】Our dog & cat flea and tick drops are combined with oregano, wormwood, black walnut, and pumpkin seeds, which contain natural flea prevention ingredients to help your pet stay balanced during flea season. Multivitamin, probiotics, and apple cider vinegar are also added to help digestion and maintain skin health, supporting skin wellness for seasonal comfort by Aids in skin and hair health and supports daily vitality. You will feel the difference when your pet's hair is radiant and looks more relaxed and at ease - we have combined the essence of nature to make your pet healthy and strong.
- 【No More Mess – A Better Way to Care】Tired of greasy topicals or hard-to-feed tablets? Our cat & dog Flea & Tick Treatment Support Drops come in a tasty bacon flavor, making daily care easy and enjoyable. Unlike sprays or shampoos, this flea treatment support drops no harsh smell—just gentle, herbal support to help your dog stay calm and comfortable during flea and tick season. We know you’d rather focus on belly rubs than battles—this makes it simple.
- 【Simplified Dog Flea Drop - Every Drop is Trustworthy】Our flea and tick protection drops contains a dropper with precise scale, so you can accurately control the amount every time you feed: under 10 pounds: 0.5 ml; 10-35 pounds: 1.25 ml; 35-75 pounds: 2.5 ml each time, 1-2 times a day, To prevent stomach upset, always take with food. Please follow safety instructions carefully. We know that precision is crucial - so every drop is designed to give you peace of mind while protecting your most precious pet.
- 【Safe, Gentle Care for Cats & Dogs】These Flea & Tick Support Drops are perfect for dogs and cats of any size, breed, or age. Made with natural plant-based ingredients, the formula is gentle, non-irritating, and suitable for daily care and long-term use. Safe for everyday use, it’s the worry-free way to help your pet stay active, comfortable, and itch-free through every season. At WEALLIN, every formula is guided by science—because lasting health is something your pet can feel, every single day. Science you can trust. Health they can feel.
- COMPARE TO K9 ADVANTIX II: Activate II uses Imidacloprid, Permethrin, and Pyriproxyfen - the same safe, fast acting active ingredients used in Advantix II for Dogs. Includes 4 monthly doses
- ACTIVELY PROTECTS YOUR DOG: Activate II is approved by veterinarians to repel and kill fleas and ticks on contact - before your dog is exposed to bites and potential flea borne illnesses
- STOP INFESTATIONS FAST: Our topical drops prevent infestations by breaking the flea life cycle - our insect growth regulator (IGR) starts killing flea eggs and larvae within 12 hours of application
- EASY TO APPLY: Simply apply to the base of your dog's neck, and the waterproof solution will travel across the skin - providing continuous protection for 30 days per application
- MADE IN AMERICA - RESULTS GUARANTEED: TevraPet Activate II is made to the quality standard we demand for our own pets. We're proud to help you protect your dog with confidence
- KILLS FLEAS & TICKS AND REPELS MOSQUITOES: Kills fleas, flea eggs, flea larvae, deer ticks and brown dog ticks on contact and repels mosquitoes before they bite
- PREVENT RE-INFESTATION: Long-lasting monthly topical flea treatment that prevents re-infestations for 1 month with dual Insect Growth Regulators (IGRs) that protect your pet and their environment
- FAST ACTING FULL BODY PROTECTION: Safe yet powerful formula spreads across the skin using your dog's natural oil to quickly travel across the coat for full body protection from head to tail
- EASY TO APPLY: Features the patented and easy-to-use Pro-Glide angled applicator with rounded edges for a softer more pleasant application experience suitable for long and short-hairded dogs
- 3 MONTHLY FLEA & TICK TREATMENTS: Contains 3 single dose tubes (1 tube per monthly application) for non-stop protection for up tp 3 months
Best Dog Flea Drops Buying Guide
Before choosing the best dog flea drops you should consider following options:
1. EPA-Approved Brands: All EPA-approved brands contain an active ingredient that kills adult fleas. These include fipronil, which kills fleas within 15 minutes of contact; and methoprene, which kills fleas on contact but also sterilizes them so they cannot reproduce.
The EPA requires that flea drops be applied to the back of the neck, where the skin is thin and absorbent.
2. New-Generation Drops: New-generation flea drops, such as those containing nitenpyram and lufenuron, are a good choice for dogs that spend time in areas where fleas are endemic, such as wooded areas.
Nitenpyram kills adult fleas and prevents flea eggs from hatching for up to 30 days. Lufenuron, which is a larvacide, breaks the life cycle of fleas by preventing newly hatched flea larvae from maturing into adults.
3. Safety: Flea drops are safe, as long as they are used according to the directions on the label.
If your dog has a bad reaction to a flea drop, you can bathe him with a flea-control shampoo and then reapply the drop.
4. How Long the Effect Lasts: When choosing flea drops, it is important to find out how long the effect will last. Some products kill fleas within hours, while others last up to a month.
5. What the Ingredients Are: Not all ingredients are safe for all dogs, so it is important to read the label and make sure it is appropriate for your dog.
Some flea drops contain lufenuron, which is not safe for dogs with a history of heartworm. Flea drops containing fipronil may not be safe for dogs weighing less than 8 pounds or puppies less than 2 pounds.
6. Price: Flea drops range in price from $7 to $15 per dose, depending on the brand and the size of the dog.
What else you should know about the best dog flea drops
1. What are the best dog flea drops on the market?
There are a few different types of flea drops on the market, so it really depends on what you are looking for. Some of the more popular brands include Frontline, Advantage, and K9 Advantix.
2. What are the active ingredients in the best dog flea drops?
There are many brands of dog flea drops, and each contains different active ingredients. Some of the most common active ingredients in dog flea drops are imidacloprid, fipronil, and pyriproxyfen.
3. Will the best dog flea drops also kill ticks?
There are a variety of dog flea and tick products on the market, so it is best to consult with your veterinarian to find the best option for your pet. Some products may kill both fleas and ticks, while others may be effective against one or the other.
4. How long will the best dog flea drops protect my dog from fleas?
Typically, the best dog flea drops will protect your dog from fleas for up to eight weeks.
Conclusion
On the market, there are numerous best dog flea drops. Hopefully, the list of the top ten best dog flea drops will save you time researching and deciding on the best one for you.