When we think about health, we think about our own. But what about our pets? Like us, dogs can suffer from digestive problems and lose their appetite when they’re not feeling well. A high-quality probiotic will help them get their appetite back and feel their best.
Not all probiotics are created equal, so it’s important to do your research before shopping. Not all probiotic supplements are safe for dogs and many are not even necessary. You also have to be careful about how you give the supplements to your dog.
To help you find the best dog probiotic supplements, we’ve turned to reviews from real dog owners on Amazon who have actually bought and used these products. These best-selling items not only have near-perfect ratings, but they also have countless glowing reviews describing why they’re so great.
Keep reading to learn more about the best dog probiotic supplements.
Our Editor’s Best Dog Probiotic Supplements Reviews
- Support Fido's Tummy - These functional soft chew supplements have a base of pumpkin and papaya (sources of enzymes) plus probiotics for digestion, bowel, and immune support to care for canine pets.
- Features Clinically Studied DE111 Probiotic - This chewable functional supplement contains DE111, a clinically studied Bacillus subtilis that supports proper digestive function and the immune system.
- Six-Strain Probiotic Powder Blend - These chewables contain six probiotics (live bacteria) that support gut function and proper gut flora for support against occasional diarrhea, gas, and bloating.
- Supports Doggy Gut Flora - Probiotic Bites help support microflora for occasional gastric distress (constipation, indigestion, gas, bloating) support and digestive tract health for your doggie.
- Treat Fido to Tasty Immunity Support - The DE111, Lactobacillus acidophilus, L. plantarum, L. brevis, L. fermentum, and L. lactis help animal immune response for small, medium, and large breeds.
- Number one probiotic supplement recommended by veterinarians (Kantar Veterinary Tracker, 2020)
- Probiotic supplement for the dietary management of puppies and adult dogs with diarrhea
- Contains a probiotic for dogs proven to promote intestinal health and balance
- Promotes a strong immune system and contains antioxidants for dogs
- Easy-to-feed dog supplement powder
- Promotes Digestive Health：Probiotic for dogs is specifically formulated to balance gut flora, dog digestive support, and help combat common digestive issues ，Pet probiotic chew able tablets can be good for you dog upset stomach remedy relief，dog gut health，remission，vomiting，gas, bloating,This probiotic for dogs gut health is naturvet probiotics and enzymes for dogs keep his digestive system in good shape,Promote absorption, full of vitality.
- Gut health for dogs is Key to Supporting Immune and Overall Health：Our dog stomach probiotics be rich in dog prebiotics not only support healthy digestion, but also help maintain regularity and supports overall health，boost your dog's immune system.Much of a dog’s wellness starts in the gut，good dog probiotic chews can effectively support immune health，improved products for dogs bad breath, provides dog probiotic and enzymes.
- High quality probiotic formula：Our probiotic chews for dogs tablets are rich in inulin and pumpkin, Inactive ingredients include brewer's yeast, natural chicken seasoning, glycerin, etc all natural ingredients carefully matched，no wheat and soy，delicious, safe and effective. It's a probiotic chew for dogs relieve remission for dogs bad breath, can improve pet mouth improves palatability andrelieve dogs probiotics for itching and yeast.
- Suitable for all dogs to help absorb essential nutrients: This probiotic chew is specially formulated for dogs and be rich in probiotic for dogs and enzymes ;Contribute to probiotic dog enzymes for dogs and help your pet get the most nutrients from their daily diet，Is probiotic chew for dogs and probiotic dog treats.Support your dog's health from gut to mouth.Keep your dog active every day.It's necessary for dog probiotic supplements
- Veterinarian Recommended, Supports Holistic Health: Pet probiotic supports holistic health, veterinarian recommended. Developed with a veterinary formula, it is free of animal protein, artificial additives, and colorings, making it safe and beneficial for dogs. Dog probiotics aids metabolism and helps improve your pet's overall digestive health. Probiotics for dogs provides excellent digestive support and nutrition, keeping your pet's life vibrant
- DIGESTIVE HEALTH SUPPORT: Enriched with pumpkin and papaya, our dog digestive support chews contain enzymes and probiotics to support gut health for dogs
- CLINICALLY PROVEN FORMULA: Featuring DE111, a scientifically validated Bacillus subtilis probiotic for dogs, these chews support digestive function and boost their immune system
- SIX-STRAIN PROBIOTIC BLEND: Each chew includes a powerful mix of six live probiotics for dogs digestive health, helping reduce occasional diarrhea, gas, and bloating in your pet
- ENHANCED GUT FLORA: Probiotic chews for dogs are designed to bolster healthy microflora, supporting dog gut health and alleviating occasional gastric discomfort
- TASTY IMMUNE BOOSTER: Includes Lactobacillus strains and DE111, this pet probiotics for dogs enhance immune response, ideal for dogs of any size, providing a delightful treat with health benefits
- DIGESTIVE ENZYMES FOR DOGS: These probiotic dog chews support dog digestive health with high-quality ingredients: Perfect for all breeds and sizes, our dog probiotics provide essential dog digestive support to keep your pup happy and healthy
- VERSATILE BENEFITS: These probiotics for dogs support dog digestive health, promote proper stool quality, and boost the immune system; With naturally occurring micro-organisms, our dog probiotic chews aid dog gut health for overall wellness
- GREAT TASTE: These probiotic chews for dogs support dog digestive health while delivering a flavor even picky eaters love; Packed with probiotics for dogs digestive health, they make the perfect dog probiotic chews for daily dog gut health support
- POWDER-FREE GUT HEALTH: No more messy powders! Support dog gut health with our probiotic dog chews; These dog digestive supplements provide the benefits of probiotics for dogs digestive health in an easy, mess-free chew—no scooping or mixing needed!
- POWERFUL BLEND: Our probiotic dog chews contain 1 billion CFUs of beneficial bacteria cultures; With prebiotic for dogs like inulin, these dog probiotics for digestive health support dog gut health, aiding dog digestive support and diarrhea relief
- Promotes Digestive Health: This probiotic for dogs is specifically formulated to maintain a healthy gut in dogs of all sizes. They help combat common issues like diarrhea, constipation, and upset stomachs.
- Advanced Probiotic & Prebiotic Formula: Each chew is packed with essential dog probiotics and digestive enzymes, along with fiber ensuring your canine companion gets the full spectrum of digestive support
- Ease Stomach Discomfort: Our pet probiotics for dogs contain ingredients known for providing relief from gas, acid, and loose stool, helping your dog feel comfortable and happy. Dog probiotic, probiotic for dogs
- Formulated for All Dogs: Created with every dog in mind, our probiotic chews for dogs are perfect for all ages and sizes - from playful puppies to wise seniors - so your loyal companion gets the nutrients they need at any stage of life
- Veterinarian Developed & USA Made: Trust in the premium quality of our dog digestive support supplement, which are formulated by veterinarians and manufactured in the USA within an FDA-registered facility
- POWERFUL FORMULA SUPPORTS GUT HEALTH & DIGESTION: Fera’s prebiotics and probiotics promote optimal gut and digestive balance. A flavorless powder - for even the pickiest eaters - contains 12 hand-selected strains, plus organic prebiotics to help with immunity, digestion, energy, metabolism, skin, coat, and dog allergy.
- ORGANIC INGREDIENTS WITH NO FILLERS: This USDA certified organic dog and cat probiotic is formulated with 12 strains (5 billion CFUs per scoop) and organic prebiotics (acacia, agave inulin and fructooligosaccharides) for a balanced digestive tract.
- VETERINARIAN FOUNDED & FORMULATED IN THE USA: Fera’s cat and dog probiotics formula is crafted by our Co-Founder, Veterinarian Dr. Dulake; our dog and cat probiotics bear the NASC (National Animal Supplement Council) quality seal, and are made in the USA, are GMP-compliant, and do not contain colors, dyes or preservatives.
- SIMPLE DIRECTIONS FOR USE: Feed as cat or dog food toppers by adding the recommended amount to dog food or cat food with the included scoop; scoop is equivalent to ½ teaspoon; under 15lbs, give ½ scoop; 16-60lbs, give 1 scoop; above 60lbs, give 2 scoops
- SAFE & EFFECTIVE DOSING: Crafted from our commitment to creating effective, honest and delicious cat and dog vitamins and supplements, this probiotic combines Eastern and Western ingredients for a holistic approach to your pet’s wellbeing.
- America's #1 Selling Probiotic for Dogs: PetLab Co.’s premium quality dog probiotics were the top-selling dog health supplement on Amazon in 2022. And owners across America are loving the benefits
- Support for Paw Licking, Itchy Skin & Healthy Yeast Levels: Each tasty probiotic chew is formulated with prebiotics and probiotics. Including 8 strains of beneficial bacteria to support the immune system and dog’s seasonal allergies
- Digestive Health: This probiotic supplement also contains Inulin (a prebiotic for dogs) and Pumpkin for dogs to support digestive health and help counter occasional diarrhea and constipation
- Manufactured in the USA & NASC Certified: Our mission is to ensure the very best quality through research and rigorous production practices. All our dog health supplies are manufactured in the USA using ingredients sourced from prime locations in the US & worldwide
- Long Term Benefits: 89% of PetLabCo. subscribers have seen benefits within 90 days* of making this part of their dog’s daily routine*. Subscribe & save today to join over 5 million PetLabCo. pet owners investing in their dog’s health & happiness daily. *Results are based on feedback from a September 2025 survey of PetLabCo. subscribers who reported using Probiotic Chews daily or almost daily for 90+ days (n=307)
- Cat and Dog Probiotics for Digestive Health - Proviable capsules contain multiple strains of beneficial bacteria, providing 5 billion colony-forming units (CFUs) to support your pet’s gut health. They also include prebiotics to encourage the growth of probiotics.
- A Healthy Gut Supports Overall Health - Probiotics help support intestinal health after imbalances, such as diet changes, food sensitivities, dietary indiscretions, or stress from travel or kenneling.
- Clinically Researched - Backed by multiple published studies, Proviable multi-strain probiotic for dogs and cats contains beneficial bacteria to help support gut health.
- Easy Administration - Incorporating Proviable probiotics into your pet’s daily routine is simple — just open the capsule and sprinkle the powder onto your pet’s food at mealtime.
- Vet Recommended Probiotic - Proviable comes from Nutramax Laboratories Veterinary Sciences Inc., the #1 Veterinarian Recommended Supplement Company*.
- New Clinically Tested Formula - With the success of our premium dog probiotics, we teamed up with experts to create a delicious new advanced salmon-flavored formula! With all the benefits of our top-selling soft pork chew plus new powerful ingredients
- Support for Paw Licking, Itchy Skin & Healthy Yeast Levels: Each tasty probiotic chew is formulated with prebiotics and probiotics. Including 8 strains of beneficial bacteria to support the immune system and dog’s seasonal allergies
- Digestive Health: This probiotic supplement also contains Inulin (a prebiotic for dogs) and Pumpkin for dogs to support digestive health and help counter occasional diarrhea and constipation
- Manufactured in the USA & NASC Certified: Our mission is to ensure the very best quality through research and rigorous production practices. All our dog health supplies are manufactured in the USA using ingredients sourced from prime locations in the US & worldwide
- Long Term Benefits: 89% of PetLabCo. subscribers have seen benefits within 90 days* of making this part of their dog’s daily routine*. Subscribe & save today to join over 5 million PetLabCo. pet owners investing in their dog’s health & happiness daily. *Results are based on feedback from a September 2025 survey of PetLabCo. subscribers who reported using Probiotic Chews daily or almost daily for 90+ days (n=307)
Best Dog Probiotic Supplements Buying Guide
Before choosing the best dog probiotic supplements you should consider following options:
1. Prebiotics and probiotics: Prebiotics and probiotics are the two types of live bacteria found in probiotic supplements.
Prebiotics help probiotics grow in the gut. They are carbohydrates that are not digested by the body but are used by probiotics for nourishment.
Probiotics are live bacteria and/or yeast that are beneficial for the gut. They help the body break down food, produce vitamins and absorb minerals. They also help keep bad bacteria from growing in the body.
Many probiotic supplements contain both prebiotics and probiotics, because both are beneficial for a dog’s digestive tract.
2. Colony-forming units (CFUs): CFU stands for colony-forming units, which is the measure of probiotic viability. It tells you how many viable bacteria are in the supplement.
The higher the CFU count, the more viable bacteria are in the product. But make sure your supplement has enough CFUs to be effective.
Some products have as little as 1 billion CFUs and others have as many as 20 billion CFUs.
3. Strains: The probiotic strains in a product will determine what benefits the product will have for your dog.
Some strains are better for boosting immunity, while others are more effective at improving digestion.
Make sure your supplement contains the right strains for the intended benefits.
4. Potency: Not all probiotic supplements are created equal. The potency of a product is important because it affects how effective the supplement will be at supporting the health of your dog’s gut.
Look for a probiotic that has enough live bacteria and/or yeast to be effective. High numbers of CFUs and enough strains to be effective are two ways to tell if a supplement has enough live bacteria and/or yeast.
5. Dosage: The dosage of a probiotic supplement is important because it affects how effective the product will be for your dog.
If the dosage is too high, the probiotic can cause side effects. If the dosage is too low, the product will have minimal benefits.
Talk to your veterinarian about the appropriate dosage for your dog. As a general rule of thumb, a probiotic supplement should have 1 billion to 5 billion live bacteria and/or yeast.
6. Time span: Most probiotics are taken daily. But some probiotics are taken for short periods of time, for example 30 days and then stopped for 30 days.
Others are taken for extended periods of time, for example 3 months and then stopped for 3 months.
Look at the label of the product you are considering to determine the time span of the supplement.
What else you should know about dog probiotic supplements
1. What is the best probiotic supplement for dogs?
There is no one-size-fits-all answer to this question, as the best probiotic supplement for dogs will vary depending on the individual dog’s needs. Some of the factors that should be considered include the dog’s age, health, and diet.
2. What are the benefits of probiotics for dogs?
There are many benefits of probiotics for dogs, including:
1. Probiotics can help improve digestion and gut health.
2. Probiotics can help reduce inflammation in the digestive tract.
3. Probiotics can help boost the immune system.
4. Probiotics can help reduce the risk of allergies.
5. Probiotics can help improve skin and coat health.
3. How do probiotics work in dogs?
Probiotics are live microorganisms that are similar to the ones that naturally live in your dog’s gut. They can help to restore the natural balance of bacteria in the gut and improve digestive and immune health.
4. What are the possible side effects of probiotic supplements in dogs?
The most common side effects of probiotic supplements in dogs are gas and bloating.
5. How do I choose the right probiotic supplement for my dog?
There is no definitive answer to this question as each dog’s individual needs may vary. However, some factors to consider when choosing a probiotic supplement for your dog include the type of probiotic strain(s) it contains, the number of live bacteria cultures present, and the delivery method (e.g. capsule, powder, etc.). You may also want to consult with a veterinarian to see if they have any specific recommendations.
Conclusion
On the market, there are numerous best dog probiotic supplements. Hopefully, the list of the top ten best dog probiotic supplements will save you time researching and deciding on the best one for you.