When we think about health, we think about our own. But what about our pets? Like us, dogs can suffer from digestive problems and lose their appetite when they’re not feeling well. A high-quality probiotic will help them get their appetite back and feel their best.
Not all probiotics are created equal, so it’s important to do your research before shopping. Not all probiotic supplements are safe for dogs and many are not even necessary. You also have to be careful about how you give the supplements to your dog.
To help you find the best dog probiotic supplements, we’ve turned to reviews from real dog owners on Amazon who have actually bought and used these products. These best-selling items not only have near-perfect ratings, but they also have countless glowing reviews describing why they’re so great.
Keep reading to learn more about the best dog probiotic supplements.
Our Editor’s Best Dog Probiotic Supplements Reviews
- Number one probiotic supplement recommended by veterinarians (Kantar Veterinary Tracker, 2020)
- Probiotic supplement for the dietary management of puppies and adult dogs with diarrhea
- Contains a probiotic for dogs proven to promote intestinal health and balance
- Promotes a strong immune system and contains antioxidants for dogs
- Easy-to-feed dog supplement powder
- Something Yummy for a Happy Tummy! - Probiotic Bites are functional soft chew dog supplements that support gut flora and immune support for your canine companion.
- Featuring DE111 - This chewable supplement contains DE111, which is a clinically studied Bacillus subtilis that supports gut health and immune system function for your doggy.
- For a Healthy Gut - Fido can continue to digest with more zest! Probiotic Bites help support gut flora and normal digestive function for small, medium, and large breeds – whether an adult or senior!
- Immune System Support - At a total of 3 billion CFU per chew, the probiotics in these Probiotic Bites provide paw-erful support for your dog's immunity.
- Good Gut Bacteria - These chewables include pawsome probiotic strains such as Lactobacillus acidophilus, L. plantarum, L. brevis, L. fermentum, and Lactococcus lactis.
- New Clinically Tested Formula - With the success of our premium dog probiotics, we teamed up with experts to create a delicious new advanced salmon-flavored formula! With all the benefits of our top-selling soft pork chew plus new powerful ingredients
- Support for Paw Licking, Itchy Skin & Healthy Yeast Levels: Each tasty probiotic chew is formulated with prebiotics and probiotics. Including 8 strains of beneficial bacteria to support the immune system and dog’s seasonal allergies
- Digestive Health: This probiotic supplement also contains Inulin (a prebiotic for dogs) and Pumpkin for dogs to support digestive health and help counter occasional diarrhea and constipation
- Manufactured in the USA & NASC Certified: Our mission is to ensure the very best quality through research and rigorous production practices. All our dog health supplies are manufactured in the USA using ingredients sourced from prime locations in the US & worldwide
- Long Term Benefits: 89% of PetLabCo. subscribers have seen benefits within 90 days* of making this part of their dog’s daily routine*. Subscribe & save today to join over 5 million PetLabCo. pet owners investing in their dog’s health & happiness daily. *Results are based on feedback from a September 2025 survey of PetLabCo. subscribers who reported using Probiotic Chews daily or almost daily for 90+ days (n=307)
- Cat and Dog Probiotics for Digestive Health - Proviable capsules contain multiple strains of beneficial bacteria, providing 5 billion colony-forming units (CFUs) to support your pet’s gut health. They also include prebiotics to encourage the growth of probiotics.
- A Healthy Gut Supports Overall Health - Probiotics help support intestinal health after imbalances, such as diet changes, food sensitivities, dietary indiscretions, or stress from travel or kenneling.
- Clinically Researched - Backed by multiple published studies, Proviable multi-strain probiotic for dogs and cats contains beneficial bacteria to help support gut health.
- Easy Administration - Incorporating Proviable probiotics into your pet’s daily routine is simple — just open the capsule and sprinkle the powder onto your pet’s food at mealtime.
- Vet Recommended Probiotic - Proviable comes from Nutramax Laboratories Veterinary Sciences Inc., the #1 Veterinarian Recommended Supplement Company*.
- Cat and Dog Probiotics for Digestive Health - Proviable capsules contain multiple strains of beneficial bacteria, providing 5 billion colony-forming units (CFUs) to support your pet’s gut health. They also include prebiotics to encourage the growth of probiotics.
- A Healthy Gut Supports Overall Health - Probiotics help support intestinal health after imbalances, such as diet changes, food sensitivities, dietary indiscretions, or stress from travel or kenneling.
- Clinically Researched - Backed by multiple published studies, Proviable multi-strain probiotic for dogs and cats contains beneficial bacteria to help support gut health.
- Easy Administration - Incorporating Proviable probiotics into your pet’s daily routine is simple — just open the capsule and sprinkle the powder onto your pet’s food at mealtime.
- Vet Recommended Probiotic - Proviable comes from Nutramax Laboratories Veterinary Sciences Inc., the #1 Veterinarian Recommended Supplement Company*.
- TOTAL GUT & BREATH SUPPORT - Advanced 5-in-1 formula combines 6 Billion CFU probiotics with digestive enzymes to balance gut flora. It effectively alleviates gas, bloating, and diarrhea while helping to freshen your dog's breath from the inside out. No more doggie breath!
- RELIEF FOR ITCHY SKIN & ALLERGIES - Boosted with Omega 3-6-9 and Pumpkin, these chews help soothe itchy skin, seasonal allergies, and yeast issues. The premium ingredients promote a shiny coat and reduce shedding, ensuring your dog looks as healthy as they feel
- PERFECT FOR PUPPIES & SENIORS - These soft, chicken-flavored chews are designed for dogs of all sizes and ages. They are easy to digest and can be easily broken into smaller pieces for puppies or senior dogs with sensitive teeth. A treat-like taste that even picky eaters love!
- NO REFRIGERATION & SHELF STABLE - Our probiotics are shelf-stable and require no refrigeration, making them perfect for travel or easy storage in your pantry. Each bottle provides 120 chews—up to a 4-month supply—offering incredible value for your pet's daily wellness
- TRUSTED USA QUALITY & PURITY - Proudly made in the USA in a GMP-certified facility and 3rd-party tested. Free from corn, wheat, soy, and dairy. We use 85% real chicken for maximum flavor and safety
- Promotes Digestive Health: This probiotic for dogs is specifically formulated to maintain a healthy gut in dogs of all sizes. They help combat common issues like diarrhea, constipation, and upset stomachs.
- Advanced Probiotic & Prebiotic Formula: Each chew is packed with essential dog probiotics and digestive enzymes, along with fiber ensuring your canine companion gets the full spectrum of digestive support
- Ease Stomach Discomfort: Our pet probiotics for dogs contain ingredients known for providing relief from gas, acid, and loose stool, helping your dog feel comfortable and happy. Dog probiotic, probiotic for dogs
- Formulated for All Dogs: Created with every dog in mind, our probiotic chews for dogs are perfect for all ages and sizes - from playful puppies to wise seniors - so your loyal companion gets the nutrients they need at any stage of life
- Veterinarian Developed & USA Made: Trust in the premium quality of our dog digestive support supplement, which are formulated by veterinarians and manufactured in the USA within an FDA-registered facility
- ADVANCED GUT & DIGESTIVE SUPPORT FOR DOGS & CATS: Supports healthy digestion, gut balance, and nutrient absorption with 12 probiotic strains and organic prebiotics—helping reduce common issues like sensitive stomachs, irregular stools, low energy, and allergy-related discomfort.
- ORGANIC PROBIOTIC POWDER WITH 12 STRAINS & PREBIOTICS: A USDA-certified organic probiotic supplement for dogs and cats featuring 5 billion CFUs per scoop plus acacia, agave inulin, and FOS to promote a balanced microbiome and overall wellness.
- IDEAL FOR PICKY EATERS & DAILY WELLNESS ROUTINES: Flavorless, easy-to-mix powder works seamlessly with any diet—perfect for pet parents looking for a stress-free alternative to pills, chews, or flavored supplements.
- EASY-TO-USE FOOD TOPPER FOR EVERYDAY FEEDING: Simply add to your pet’s food at home—includes scoop for precise dosing (½ scoop under 15 lbs, 1 scoop 16–60 lbs, 2 scoops 60+ lbs) to support consistent daily gut health.
- VET-FORMULATED, SAFE & EFFECTIVE HOLISTIC SUPPORT: Developed by our Co-Founder, veterinarian Dr. Dulake, and made in the USA in GMP-certified facilities, this NASC-approved formula combines Eastern and Western ingredients for safe, effective, long-term wellness.
- DIGESTIVE ENZYMES FOR DOGS: These probiotic dog chews support dog digestive health with high-quality ingredients: Perfect for all breeds and sizes, our dog probiotics provide essential dog digestive support to keep your pup happy and healthy
- VERSATILE BENEFITS: These probiotics for dogs support dog digestive health, promote proper stool quality, and boost the immune system; With naturally occurring micro-organisms, our dog probiotic chews aid dog gut health for overall wellness
- GREAT TASTE: These probiotic chews for dogs support dog digestive health while delivering a flavor even picky eaters love; Packed with probiotics for dogs digestive health, they make the perfect dog probiotic chews for daily dog gut health support
- POWDER-FREE GUT HEALTH: No more messy powders! Support dog gut health with our probiotic dog chews; These dog digestive supplements provide the benefits of probiotics for dogs digestive health in an easy, mess-free chew—no scooping or mixing needed!
- POWERFUL BLEND: Our probiotic dog chews contain 1 billion CFUs of beneficial bacteria cultures; With prebiotic for dogs like inulin, these dog probiotics for digestive health support dog gut health, aiding dog digestive support and diarrhea relief
- COMPLETE GUT & DIGESTIVE HEALTH SUPPORT - IsA Probiotics for dogs designed to support gut health and digestion. This dog probiotic powder helps maintain healthy stool quality and digestive balance for dogs with sensitive stomachs.
- 6 BILLION CFUs FROM DOG-SPECIFIC PROBIOTIC STRAINS - Dog probiotics made with 6B CFUs from 4 dog-specific probiotic strains. IsA dog probiotic supplements that deliver live, beneficial bacteria formulated specifically for canine gut health.
- FOR DOGS ON ANTIBIOTICS THAT NEED GUT RESTORATION – usedFor dog probiotics for diarrhea and digestive recovery, this probiotic for dogs gut health restores beneficial bacteria lost during medication or illness.
- PREBIOTICS + FIBER FOR DIGESTIVE BALANCE – capableOf delivering dog prebiotics and probiotics with organic pumpkin powder for dogs and inulin from Jerusalem artichoke to nourish beneficial gut bacteria daily.
- TASTY, EASY-TO-SERVE POWDER FOOD TOPPER: cause of dogs refusing supplements is poor taste and hard-to-serve formats — ours isA dog food toppers probiotic powder capableOf mixing easily into wet or dry food. Works for dogs of all ages, breeds, and sizes.
Best Dog Probiotic Supplements Buying Guide
Before choosing the best dog probiotic supplements you should consider following options:
1. Prebiotics and probiotics: Prebiotics and probiotics are the two types of live bacteria found in probiotic supplements.
Prebiotics help probiotics grow in the gut. They are carbohydrates that are not digested by the body but are used by probiotics for nourishment.
Probiotics are live bacteria and/or yeast that are beneficial for the gut. They help the body break down food, produce vitamins and absorb minerals. They also help keep bad bacteria from growing in the body.
Many probiotic supplements contain both prebiotics and probiotics, because both are beneficial for a dog’s digestive tract.
2. Colony-forming units (CFUs): CFU stands for colony-forming units, which is the measure of probiotic viability. It tells you how many viable bacteria are in the supplement.
The higher the CFU count, the more viable bacteria are in the product. But make sure your supplement has enough CFUs to be effective.
Some products have as little as 1 billion CFUs and others have as many as 20 billion CFUs.
3. Strains: The probiotic strains in a product will determine what benefits the product will have for your dog.
Some strains are better for boosting immunity, while others are more effective at improving digestion.
Make sure your supplement contains the right strains for the intended benefits.
4. Potency: Not all probiotic supplements are created equal. The potency of a product is important because it affects how effective the supplement will be at supporting the health of your dog’s gut.
Look for a probiotic that has enough live bacteria and/or yeast to be effective. High numbers of CFUs and enough strains to be effective are two ways to tell if a supplement has enough live bacteria and/or yeast.
5. Dosage: The dosage of a probiotic supplement is important because it affects how effective the product will be for your dog.
If the dosage is too high, the probiotic can cause side effects. If the dosage is too low, the product will have minimal benefits.
Talk to your veterinarian about the appropriate dosage for your dog. As a general rule of thumb, a probiotic supplement should have 1 billion to 5 billion live bacteria and/or yeast.
6. Time span: Most probiotics are taken daily. But some probiotics are taken for short periods of time, for example 30 days and then stopped for 30 days.
Others are taken for extended periods of time, for example 3 months and then stopped for 3 months.
Look at the label of the product you are considering to determine the time span of the supplement.
What else you should know about dog probiotic supplements
1. What is the best probiotic supplement for dogs?
There is no one-size-fits-all answer to this question, as the best probiotic supplement for dogs will vary depending on the individual dog’s needs. Some of the factors that should be considered include the dog’s age, health, and diet.
2. What are the benefits of probiotics for dogs?
There are many benefits of probiotics for dogs, including:
1. Probiotics can help improve digestion and gut health.
2. Probiotics can help reduce inflammation in the digestive tract.
3. Probiotics can help boost the immune system.
4. Probiotics can help reduce the risk of allergies.
5. Probiotics can help improve skin and coat health.
3. How do probiotics work in dogs?
Probiotics are live microorganisms that are similar to the ones that naturally live in your dog’s gut. They can help to restore the natural balance of bacteria in the gut and improve digestive and immune health.
4. What are the possible side effects of probiotic supplements in dogs?
The most common side effects of probiotic supplements in dogs are gas and bloating.
5. How do I choose the right probiotic supplement for my dog?
There is no definitive answer to this question as each dog’s individual needs may vary. However, some factors to consider when choosing a probiotic supplement for your dog include the type of probiotic strain(s) it contains, the number of live bacteria cultures present, and the delivery method (e.g. capsule, powder, etc.). You may also want to consult with a veterinarian to see if they have any specific recommendations.
Conclusion
On the market, there are numerous best dog probiotic supplements. Hopefully, the list of the top ten best dog probiotic supplements will save you time researching and deciding on the best one for you.